RESPONSE OF PERIPHERAL BLOOD INDICATORS IN PATIENTS WITH LONG BONE FRACTURES AGAINST COVID-19
DOI:
https://doi.org/10.32689/2663-0672-2023-3-1Keywords:
Patients, bone fractures, COVID-19, diagnostics, peripheral bloodAbstract
Introduction: In the spring of 2020, Ukraine, like the rest of the world, faced a new coronavirus infection, COVID-19. Diagnostic measures are a key link in the success of treatment of victims with long bone fractures against the background of COVID-19. The aim of our study was to determine the level and dynamics of peripheral blood diagnostic tests that could characterize the course of COVID-19 in patients with limb fractures and their impact on the early diagnosis of complications in this category of patients. Materials and methods: 289 cases of skeletal bone fractures treated at the "Kyiv City Clinical Hospital of Emergency Medical Care" from March 2020 to February 2021 and meeting the criteria for inclusion in the study were analyzed. Results: the conducted study of the reaction of peripheral blood in patients with long bone fractures against the background of COVID-19 indicated that in the majority of patients of the main array, the reaction of the red part of blood did not exceed the reference indicators, but was prone to thickening. Among the patients of the main array, leukocytosis with a significant shift to the left was noted, which was found in 70.1% of cases. Such a leukocyte reaction is the result of the impact of the body's sharp inflammatory reaction to the COVID-19 virus. In patients with COVID-19, suppression of lymphocyte growth of white blood was observed, which was manifested in 84.1% of patients of the main group, as well as in an increase in the average levels of eosinophils, basophils and monocytes. Thrombocytosis was observed in 59.9% of patients, which indicates the risk of thromboembolic complications among patients of the experimental group. Conclusions: In patients with fractures against the background of COVID-19, a clear and reliable reaction of red blood to the infectious process and trauma in the form of an increased level of hemoglobin and erythrocytes, leukocytosis, lymphopenia, eosinophilia, basophilia and monocytosis was revealed. The possible development of thromboembolic complications was indicated by the presence of thrombocytosis in the majority of patients with long bone fractures against the background of COVID-19.
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