THE FEATURES OF HEMOPOESYS AND MODERN APPROACH OF ABILITATION IN PERINATAL PATHOLOGY СHILDREN

Abstract

Background.There is significant rising of morbidity rate and decreasing amount among children population in Ukraine. The count of preterm and low body weight newborns steadily grows up too. The aim of article is to review the current knowledge regarding the perynatal pathology among the reasons of morbidity and an abilitationrheabilitation strategy of postnatal development support. Materials and methods. We have conducted a literature search on the PubMed/MEDLINE, Google Scholar databases with the keyword “perynatal pathology”, “newborns”, “hemathogycal index”, “abilitation”. We have made retrospective analyses of the newborns result general blood tests and calculated of hemathogycal index (leukocyte index, neutrophil-to-lymphocyte ratio and neutrophil-tomonocyte ratio) according to data of perinatal patology and indicated the clinical features of newborns. Results and discussion. The mean leukocyte index in the study group was 0.12 [maxmum (max) 0.13, minimum (min) 0.1] with a standart deviation (SD) 0.01, while in the control group it was 0.13 [ max 0.17, min 0.11], SD 0.016; the Mann-Whitney U-test result was 151.5 (p≤0.05). The mean neutrophil-to-monocyte ratio in the study group was 3.77 [ max 4.38, min 3.16], SD 0.38, in the control group it was 4.98 [ max 5.8, min 4.25], SD 0.55; the Mann- Whitney U-test result was 677.0 (p≤0.05). The mean value of the neutrophil-to-lymphocyte ratio in the study group was 0.7 [ max 0.86, min 0.53], SD 0.1, in the control group it was 0.57 [ max 0.61, min 0.54], SD 0.26; the Mann- Whitney U-test result was 805.0. There was no statistically significant difference between the value of the neutrophilto- lymphocyte ratio in the both groups. Early intervention and handling are necessary and pathophysiologically justified for phycomotor development and grove up of perinal pathology children.