THE IMPACT OF ELECTRONIC NICOTINE DELIVERY SYSTEMS ON ORAL HEALTH
DOI:
https://doi.org/10.32689/2663-0672-2025-2-18Keywords:
electronic cigarettes, oral health, caries, periodontal diseasesAbstract
Introduction. Despite the well-known harms of traditional smoking, there is a growing popularity of electronic cigarettes, especially among young people, which raises concerns about their impact on health. This article explains the mechanism of action of electronic cigarettes and the composition of their aerosols, their effect on the oral microbiome, the risk of developing caries and periodontal diseases, as well as changes in saliva composition and its antioxidant properties. The article also discusses the impact of vaping on orthodontic treatment and the potential for injuries caused by device explosions.Objective. To investigate and establish a correlation between the use of electronic cigarettes and changes in the oral cavity that result from their use, based on the analysis of previous scientific data.Materials and Methods. The study involved the analysis of scientific publications available on research platforms such as Google Scholar and PubMed. Bibliosemantic methods and structural-logical analysis were employed. The methodological foundation of the research was a systematic approach. Conclusions. Based on the analysis of existing studies, the need for further in-depth research into the effects of electronic cigarette use on oral health is emphasized, as well as the importance of informing the population, especially the youth, about the associated risks.
References
Albadrani M. S, Tobaiqi M. A., Muaddi M. A., Eltahir H. M., Abdoh E. S. et al. A global prevalence of electronic nicotine delivery systems (ENDS) use among students: a systematic review and meta-analysis of 4,189,145 subjects. BMC Public Health. 2024. Vol. 24(1). P. 3311.
Almeida-da-Silva C.L.C., Matshik Dakafay H., O'Brien K., Montierth D., Xiao N., Ojcius D. M. Effects of electronic cigarette aerosol exposure on oral and systemic health. Biomed J. 2021. Vol. 44(3). P. 252–259.
Andrikopoulos G., Farsalinos K., Poulas K. Electronic Nicotine Delivery Systems (ENDS) and Their Relevance in Oral Health. Toxics. 2019. Vol. 7(4). P. 61.
Auschwitz E., Almeda J., Andl C. D. Mechanisms of E-Cigarette Vape-Induced Epithelial Cell Damage. Cells. 2023. Vol. 12(21). P. 2552.
Cichońska D., Kusiak A., Goniewicz M. L. The Impact of E-Cigarettes on Oral Health-A Narrative Review. Dent J (Basel). 2024 Dec 10. 12(12). P.404. doi: 10.3390/dj12120404.
Cichońska D., Kusiak A., Kochańska B., Ochocińska J., Świetlik D. Influence of Electronic Cigarettes on Selected Physicochemical Properties of Saliva. Int J Environ Res Public Health. 2022. Vol. 19(6). P. 3314.
Corey C. G., Chang J. T., Rostron B. L. Electronic nicotine delivery system (ENDS) battery-related burns presenting to US emergency departments, 2016. Inj Epidemiol. 2018. Vol. 5(1). P. 4.
Croome K. P. Introducing Machine Perfusion into Routine Clinical Practice for Liver Transplantation in the United States: The Moment Has Finally Come. J. Clin. Med. 2023. Vol. 12(3). P. 909.
Ebersole J., Samburova V., Son Y., Cappelli D. et al. Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity. Tob Induc Dis. 2020. Vol. 18. P. 41.
Fagan P., Pokhrel P., Herzog T. A., Moolchan E. T., Cassel K. D., Franke A. A. Sugar and aldehyde content in flavored electronic cigarette liquids. Addictive Carcinogens Workgroup. Nicotine and Tobacco Research. 2018. Vol. 20(8). P. 985–992.
Farsalinos K., Barbouni A., Niaura R. Smoking, vaping and hospitalization for COVID-19. Qeios. 2020. doi: 10.32388/ z69o8a.9.
Harrison R., Hicklin Jr. D. Electronic cigarette explosions involving the oral cavity. The Journal of the American Dental Association. 2016. Vol. 147(11). P. 891–896.
Iacob A. M., Escobedo Martínez M. F., Barbeito Castro E., Junquera Olay S., Olay García S., Junquera Gutiérrez L. M. Effects of Vape Use on Oral Health: A Review of the Literature. Medicina (Kaunas). 2024. Vol. 60(3). P. 365.
Jeong W., Choi D. W., Kim Y. K., Lee H. J., Lee S. A., Park E. C., Jang S. I. Associations of electronic and conventional cigarette use with periodontal disease in South Korean adults. J Periodontol. 2020. Vol. 91(1). P. 55–64.
Jyothish S., Athanasiou A. E., Makrygiannakis M. A., Kaklamanos E. G. Effect of nicotine exposure on the rate of orthodontic tooth movement: A meta-analysis based on animal studies. PLoS One. 2021. Vol. 16(2). P. e0247011.
Kim S. A., Smith S., Beauchamp C., Song Y., Chiang M. et al. Cariogenic potential of sweet flavors in electronic-cigarette liquids. PLoS One. 2018. Vol. 13(9). P. e0203717.
Krishnan-Sarin S., Morean M., Kong G., Bold K. W., Camenga D. R., Cavallo D. A., Simon P., Wu R. E-Cigarettes and "Dripping" Among High-School Youth. Pediatrics. 2017. Vol. 139(3). P. e20163224.
Li Y., Jacox L. A., Little S. H., Ko C. C. Orthodontic tooth movement: The biology and clinical implications. The Kaohsiung Journal of Medical Sciences. 2018. Vol. 34(4). P. 207–214.
Meikle M. C. The tissue, cellular, and molecular regulation of orthodontic tooth movement: 100 years after Carl Sandstedt. The European Journal of Orthodontics. 2006. Vol. 28(3). P. 221–240.
Michelogiannakis D., Rossouw P.E., Al-Shammery D., Akram Z., Khan J., Romanos G. E., Javed F. Influence of nicotine on orthodontic tooth movement: A systematic review of experimental studies in rats. Archives of Oral Biology. 2018. Vol. 93. P. 66–73.
Pushalkar S., Paul B., Li Q., Yang Y., Vasconcelos R, Makwana S, Saxena D. Electronic cigarette aerosol modulates the oral microbiome and increases risk of infection. iScience. 2020. Vol. 23(3).
Rathnayake S., Jayakody S., Wannisinghe P., Wijayasinghe D., Jayathilaka R., Madhavika N. Macroeconomic factors affecting FDI in the African region. PLoS One. 2023. Vol. 18(1). P. e0280843.
Sharma K., Jha R.K. Impact of Vaping on Lungs: An Indian Prospect. Cureus. 2023. Vol. 15(11). P. e48281.
Stämpfli M.R., Anderson G.P. How cigarette smoke skews immune responses to promote infection, lung disease and cancer. Nature Reviews Immunology. 2009. Vol. 9(5). P. 377–384.
Wills C. A., Carrico C. Use of an RN-Initiated Protocol for Recognition, Management, and Documentation of Intradialytic Hypotension in Patients with End Stage Kidney Disease on In-Center Hemodialysis: A Quality Improvement Project. Nephrol. Nurs. J. 2022. Vol. 46(6). P. 495–504.
Xu F., Aboseria E., Janal M. N., Pushalkar S., Bederoff M. V., Vasconcelos R., Saxena D. Comparative effects of E-cigarette aerosol on periodontium of periodontitis patients. Frontiers in Oral Health. 2021. Vol. 2. P. 729144.
Xu F., Pushalkar S., Lin Z., Thomas S. C., Persaud J. K., Sierra M. A., Saxena D. Electronic cigarette use enriches periodontal pathogens. Molecular Oral Microbiology. 2022. Vol. 37(2). P. 63–76.
